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Setsuo Hirohashi Selected Research

Cadherins (E-Cadherin)

4/2011Significance of dysadherin and E-cadherin expression in differentiated-type gastric carcinoma with submucosal invasion.
10/2010Comparison of the dysadherin and E-cadherin expression in primary lung cancer and metastatic sites.
9/2009Tyrosine-phosphorylation of the 12th armadillo-repeat of beta-catenin is associated with cadherin dysfunction in human cancer.
1/2008Differential expression of dysadherin in papillary thyroid carcinoma and microcarcinoma: correlation with E-cadherin.
1/2008A new formula for predicting liver metastasis in patients with colorectal cancer: immunohistochemical analysis of a large series of 439 surgically resected cases.
1/2007Dysadherin expression as a significant prognostic factor and as a determinant of histologic features in synovial sarcoma: special reference to its inverse relationship with E-cadherin expression.
7/2006Chemokine (C-C motif) ligand 2 mediates the prometastatic effect of dysadherin in human breast cancer cells.
7/2006[E-cadherin cell adhesion system in human cancer].
6/2006Expression patterns of dysadherin and E-cadherin in lymph node metastases of colorectal carcinoma.
2/2006Dysadherin expression in head and neck squamous cell carcinoma: association with lymphangiogenesis and prognostic significance.
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Setsuo Hirohashi Research Topics

Disease

103Neoplasms (Cancer)
04/2011 - 01/2002
35Neoplasm Metastasis (Metastasis)
04/2011 - 01/2002
30Carcinogenesis
09/2009 - 01/2002
20Colorectal Neoplasms (Colorectal Cancer)
08/2010 - 08/2002
20Hepatocellular Carcinoma (Hepatoma)
03/2010 - 01/2002
16Adenocarcinoma
10/2010 - 04/2002
14Carcinoma (Carcinomatosis)
04/2011 - 06/2002
12Lung Neoplasms (Lung Cancer)
11/2010 - 07/2002
11Squamous Cell Carcinoma (Epidermoid Carcinoma)
10/2010 - 01/2002
10Pancreatic Neoplasms (Pancreatic Cancer)
01/2011 - 10/2004
8Stomach Neoplasms (Stomach Cancer)
03/2011 - 03/2003
7Liver Neoplasms (Liver Cancer)
12/2008 - 01/2002
6Lymphatic Metastasis
04/2011 - 07/2003
6Precancerous Conditions
07/2006 - 07/2002
6Breast Neoplasms (Breast Cancer)
07/2006 - 09/2002
6Colonic Neoplasms (Colon Cancer)
09/2005 - 03/2002
5Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
12/2008 - 08/2003
5Adenocarcinoma of Lung
07/2007 - 03/2002
4Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
01/2010 - 06/2002
4Small Cell Lung Carcinoma (Small Cell Lung Cancer)
10/2009 - 06/2003
4Esophageal Neoplasms (Esophageal Cancer)
09/2009 - 11/2005
4Esophageal Squamous Cell Carcinoma
05/2009 - 01/2004
4Renal Cell Carcinoma (Grawitz Tumor)
02/2009 - 02/2003
4Chromosomal Instability (Chromosome Stability)
12/2007 - 07/2002
4Transitional Cell Carcinoma
07/2005 - 04/2003
4Adenoma (Adenomas)
09/2003 - 04/2002
3Osteosarcoma (Osteogenic Sarcoma)
05/2010 - 09/2008
3Squamous Cell Carcinoma of Head and Neck
09/2009 - 01/2002
3Synovial Sarcoma (Synovioma)
09/2008 - 08/2002
3Sarcoma (Soft Tissue Sarcoma)
09/2008 - 08/2002
3Ductal Carcinoma
06/2006 - 06/2005
3Urinary Bladder Neoplasms (Bladder Cancer)
07/2005 - 04/2005
3Fibrosis (Cirrhosis)
11/2004 - 07/2002
3Chronic Hepatitis (Chronic Active Hepatitis)
11/2004 - 07/2002
2Small Cell Carcinoma
10/2010 - 09/2004
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2010 - 06/2003
2Melanoma (Melanoma, Malignant)
03/2010 - 04/2005
2Neutropenia
05/2009 - 03/2008
2Endometrial Neoplasms (Endometrial Cancer)
03/2009 - 06/2007
2Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
09/2008 - 09/2002
2Leiomyosarcoma
09/2008 - 08/2006
2Ovarian Neoplasms (Ovarian Cancer)
07/2008 - 08/2007
2Papillary Carcinoma
01/2008 - 09/2003
2Malignant Fibrous Histiocytoma
08/2006 - 08/2002
2Liposarcoma
10/2005 - 08/2002

Drug/Important Bio-Agent (IBA)

54Proteins (Proteins, Gene)FDA Link
01/2011 - 01/2002
30Cadherins (E-Cadherin)IBA
04/2011 - 01/2002
25beta CateninIBA
09/2009 - 04/2002
20DNA (Deoxyribonucleic Acid)IBA
12/2009 - 07/2002
17Biomarkers (Surrogate Marker)IBA
01/2011 - 02/2004
15Biological ProductsIBA
11/2010 - 06/2002
14Glycoproteins (Glycoprotein)IBA
04/2011 - 01/2002
11MethyltransferasesIBA
12/2007 - 07/2002
10Messenger RNA (mRNA)IBA
04/2010 - 07/2002
10Indicators and Reagents (Reagents)IBA
09/2008 - 08/2002
9ProteomeIBA
01/2011 - 09/2003
9ErbB Receptors (EGF Receptor)IBA
07/2007 - 01/2002
7KalininIBA
09/2004 - 01/2002
6Phosphotransferases (Kinase)IBA
08/2010 - 08/2003
5Peptides (Polypeptides)IBA
01/2011 - 07/2004
5Blood Proteins (Serum Proteins)IBA
06/2007 - 10/2005
4EnzymesIBA
06/2010 - 12/2003
4OligonucleotidesIBA
03/2010 - 02/2003
4Monoclonal AntibodiesIBA
01/2010 - 05/2003
4Protein Isoforms (Isoforms)IBA
09/2008 - 03/2002
4A-factor (Streptomyces)IBA
07/2008 - 12/2005
4Complementary DNA (cDNA)IBA
03/2007 - 01/2002
4CateninsIBA
10/2005 - 07/2002
3AntigensIBA
03/2011 - 07/2005
3Small Interfering RNA (siRNA)IBA
06/2010 - 09/2008
3GemcitabineFDA Link
04/2010 - 05/2009
3Tyrosine (L-Tyrosine)FDA Link
09/2009 - 07/2003
3Microfilament Proteins (Actin Binding Proteins)IBA
09/2008 - 01/2005
3TCF Transcription FactorsIBA
04/2008 - 03/2003
3hydrogen sulfite (bisulfite)IBA
07/2006 - 02/2004
3Coloring Agents (Dyes)IBA
03/2006 - 04/2005
3Tumor Biomarkers (Tumor Markers)IBA
01/2006 - 09/2004
3Galectin 3 (LGALS3)IBA
06/2003 - 08/2002
2LigandsIBA
01/2011 - 01/2011
2CXC ChemokinesIBA
01/2011 - 01/2011
2Cell Adhesion MoleculesIBA
01/2011 - 06/2002
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
11/2009 - 10/2009
2AntibodiesIBA
09/2009 - 09/2006
2TransglutaminasesIBA
09/2009 - 05/2009
2Carrier Proteins (Binding Protein)IBA
09/2009 - 12/2008
2RNA (Ribonucleic Acid)IBA
12/2008 - 07/2004
2alpha-Fetoproteins (alpha-Fetoprotein)IBA
12/2008 - 09/2004
2TropomyosinIBA
09/2008 - 08/2006
2Irinotecan (Camptosar)FDA LinkGeneric
03/2008 - 06/2005
2ChromatinIBA
12/2007 - 11/2002
2Proliferating Cell Nuclear Antigen (PCNA)IBA
06/2007 - 02/2004
2ActininIBA
12/2006 - 08/2006
2Membrane Glycoproteins (Membrane Glycoprotein)IBA
07/2006 - 10/2004
2Cysteine (L-Cysteine)FDA Link
03/2006 - 04/2005
2Fluorescent Dyes (Fluorescent Probes)IBA
01/2006 - 09/2003

Therapy/Procedure

13Therapeutics
04/2010 - 06/2003
11Lasers (Laser)
06/2007 - 04/2002
6Drug Therapy (Chemotherapy)
05/2010 - 11/2005
2Neoadjuvant Therapy
03/2010 - 12/2009
2Radiotherapy
11/2005 - 09/2002